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31 Mail & Guardian August 19 to 25 2016
        TUT Center for Tissue Engineering
       News

       A gift that





       will leave a





       lasting legacy






       An expert in organ and tissue donation
       explains the power of transplants



       Willa de Ruyter               sue donation, tissue transplants play
                                     a vital role in improving the quality
               o leave a lasting legacy   of life for ordinary South Africans.
               is probably one of the   This includes healing opportunities   Cleo Ndhlovu, manager of the Tshwane University of Technology’s Centre for Tissue Engineering, with some of
               most deep-seated human   for patients who suffer from skel-  the centre’s staff (above). Photo: Amanda van Rensburg
       ‘Tdesires. Hence, giving      etal conditions, repairing the sight
       part of oneself through organ and   of people who may otherwise suf-
       tissue donation is a gift that never   fer permanent blindness, saving the   Tear of Hope
       ceases to yield rewards. Unlike a   lives of burn victims and providing   “Taking hands with the glass
       gift voucher that eventually gets   treatment options for people with   experts at TUT’s faculty of the arts,
       used up, this is a gift that becomes   congenital heart defects.    the Tear of Hope, which has pretty
       part of another person’s life.” This   “Donors come from all walks of   much become our signature, was
       is the opinion of Cleo Ndhlovu,   life, but unfortunately only a small   created as a reminder to donor
       manager of the Tshwane University   segment of the South African popu-  families of their wonderful gifts
       of Technology’s Centre for Tissue   lation are currently registered as   to mankind. Every donor family
       Engineering (CTE) in Pretoria.  donors. This may be due to cultural   receives an exquisite, hand-crafted,
        With a focus on August as Organ   and religious factors, but I strongly   solid glass teardrop to say thank
       Donor Month, the Mail & Guardian   suspect it is more due to a lack of   you, and to demonstrate the hope
       talked to Ndhlovu about the impor-  information. In addition to the CTE’s   and new life that was made possi-
       tance of organ and tissue donation,   own efforts to educate the public   ble through their sacrifice of tears.”
       as well as the amazing work done   on the responsibility of becoming
       at the CTE, which celebrates its   donors, we have always worked
       14th anniversary this year. Her love   closely with the Organ Donor
       for this challenging sector of the   Foundation (ODF), to reach people
       health industry is clear when she   of all communities and to provide
       talks about the life-changing differ-  them with information to under-
       ence the transplant of tissue — such   stand the benefits of donation.”
       as a cornea, a bone allograft or the   She explains that a formal partner-
       treatment of serious burn wounds   ship agreement signed between the
       through the use of cadaveric skin —   cadaveric tissue banks of CTE, Bone
       can make.                     SA and ODF in July 2016 will go a
                                     long way towards increasing market-
       What is the Centre for Tissue   ing opportunities and resources to
       Engineering?                  escalate the general awareness about
       The  CTE  was  established  in   all forms of donation.      To register as an organ and tissue
       September 2002, following an agree-  “We are excited about the agree-  donor please visit www.odf.org.za or
       ment between TUT and Bone SA’s   ment, which will allow for more   www.tissuedonation.org.za or call the
       Professor Mariëtte Lowes, dean of   integrated and centralised market-  toll-free number at: 0800 22 66 11
       the faculty of science at the time, and   ing and advertising campaigns to
       Mrs Martina Lutz of Bone SA, who   create awareness of the vital ser-
       signed the deal to form the second   vices all these organisations offer.
       human bone bank in South Africa.  In addition, the logistics of liaising   “The major challenge we face is   tle is already half won.  to patients in state hospitals.”
        The CTE was established to make   with donor families, referring poten-  inadequate financial resources for   “Another very useful practice in my   The best solution to this problem
       more bone tissue available in the   tial donors, as well as registering   marketing the importance of organ   own life is to find mentors for differ-  is cadaveric human skin. Only a few
       country for transplants, but t soon   to become a donor, will be central-  and tissue donation to the general   ent areas of my life. To have someone   strips from the very top layer of skin
       developed into a mature, multi-tis-  ised in one database in future. This   public. Only about 200 000 people,   to talk to and to use as a soundboard   can be procured from organ and tis-
       sue bank with a strong professional   means that whether people register   from the total South African popu-  is invaluable for providing guidance,   sue donors, which can then be used
       reputation, both locally and interna-  on www.tissuedonation.org.za or on   lation of about 54 million, are cur-  both professionally and in your per-  very effectively on burn victims.
       tionally. Located at the CSIR in the   www.odf.org.za, all these registra-  rently registered as organ and tis-  sonal life,” says Ndhlovu.  Although there are a number of
       East of Pretoria, the CTE operates   tions will go to a central database.”   sue donors. We have a massive task         transplant centres, as well as eye and
       in all provinces throughout South                           ahead of us in educating people  What are some of the CTE’s   tissue banks around South Africa,
       Africa to procure human tissue from  How do you ensure adherence   about the topic.       milestones?                   there has never been a successful
       cadaveric donors. It provides tissue  to ethical standards, and what   “At a national level, there is legisla-  “Over the past five years, the CTE   long-term skin-banking program.
       allografts to private and state hospi-  are some of the challenges the   tion that guides our work, but there   has been inundated with pleas from   The treatment of burns with
       tals, clinics and surgeons.   CTE has to deal with?         is no official policy on organ dona-  surgeons and burn units around the   cadaveric skin has a number of
        According to Ndhlovu, it was ini-  “Because of the nature of our busi-  tion, nor is there a national system   country to assist with the banking   advantages for the recipient. The
       tially quite challenging to establish   ness, we have to be very aware of our   that facilitates the donation process.   of skin for the treatment of burn vic-  treatment process is far less trau-
       the CTE as a role player in the indus-  conduct at all times, says Ndhlovu.  The result is that when a registered   tims. The majority of patients who   matic and painful than treatment
       try. However, by 2005, and under   “Confidentiality is of the utmost   donor passes away, we are often not   require skin are state patients, who   with synthetic dressings, less scar-
       the directorship of Professor Danie   importance. We often deal with   aware of the fact, which can result in   are more often than not the victims   ring occurs and the cost saving is
       du Toit and Dr Nicolaas Duneas, the   sensitive information and it is vital   the tissue being lost.  of shack fires that frequently result   massive.
       CTE gained substantial support and   that we follow the correct protocols   “The partnership agreement   in life threatening burns. Although   “One of the biggest challenges in
       donor numbers have since increased   when families and potential donors   between CTE and the ODF, which   there are no financial advantages to   providing skin in adequate quanti-
       steadily.                     share such information with us. We   I alluded to earlier, is aimed at   be gained through skin procurement   ties is the shortage of organ and tis-
        “Although the CTE’s primary focus   always act within the law — we treat   addressing and alleviating these   and distribution, the CTE and Bone   sue donors. Every person in South
       is on the retrieval, processing and   the body of every donor with utmost   issues.”      SA felt morally obliged to make a   Africa can make a difference, and we
       storage of bone, cartilage, tendons,   respect — as if it were a member of                financial commitment and take on   appeal to the public to make a deci-
       corneas,  skin  and  cardiovascular   our own family.       In addition to being organ    the challenge to help these ordinary   sion in favour of donation after their
       tissue for implant, transplant and   “We are sensitive to the rules of  donor month,  August  is   South Africans,” says Ndhlovu.   death,” says Ndhlovu.
       therapeutic purposes, human tis-  other organisations or companies  Women’s Month. What is your   “The launch of the first skin bank-  Early in 2015 cardiovascular tissue
       sue research and development func-  who assist us in the cause of organ  message to the young women   ing programme in South Africa   procurement was added to the CTE
       tions are also provided for internal   and tissue donation. We value the  of this country?  in April 2016 was probably one of   profile, following an agreement with
       role players as well external industry   health and lives of recipients and will   “Women face many challenges and   the most notable highlights for the   Netcells, which does the actual cryo-
       partners. The CTE is the only true   never compromise on quality and   have  to  juggle  their  professional,   CTE.  The programme is aimed at   preservation of the valves.
       multi-disciplinary tissue bank in the   safety.             family and social lives, as well as   alleviating the dire need for skin   “We are extremely proud of the
       country,” says Ndhlovu.        “As far as the retrieval of tissue is   other aspects of daily life. My advice   to treat burn victims and prevent   progress the CTE has made in 14
                                     concerned, our retrieval officers are   is to surround yourself with sup-  the death of victims. These deaths   years and take courage from the
       Why would people become       compelled to adhere to very strict   portive, like-minded people who   occur not only because of the sever-  TUT slogan ‘We Empower People’.
       donors?                       locally and internationally recog-  understand where you are heading   ity of the burns, but because there   Looking at the work of the CTE, this
       Ndhlovu explains that, although   nised procedures, against which they   and who can provide the support you   are no effective, affordable syn-  slogan rings true in every sense of
       there is little awareness about tis-  are continually evaluated.  need to succeed. In this way the bat-  thetic treatment options available   the word,” concludes Ndhlovu.
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